ABSTRACT
Since laparoscopic cholecystectomy(LC) was first introduced in early 1990 in Korea, LC is now widely used with an acknowledgement of the benefits of LC.The author retrospectively analyzed 120 patients who were treated by LC and 40 patients who were treated by open cholecystectomy(OC), at the Department of Surgery, Kwang Hye Hospital from Jan. 1992 to July 1995. For the statistical analysis of the variables, student's t-test and ANOVA F-test were used to assess the differences between two groups(p value = 0.05). The obtained results were as follows. 1. The mean age and sex ratio(M:F) between LC and OC group were 48.3-years-old and 1:1.45, 57.6-years-old and 1:3.4, respectively. 2. Associated diseases were observed in 62 patients (51.7%) of the LC group and 23 patients (57.5%) of the OC group. Peptic ulcer and DM were most frequent, respectively. 3. 20 patients (16.7%) had a previous abdominal operation, with appendectomy, the most frequent among them. 4. The operation times(p=0.05), hospitalization stay(p=0.0001), and postoperative hospitalization stay(p=0.0001) were significantly shorter in the LC group than in the OC group. 5. In the preoperative, intraoperative, and postoperative ABGA of the LC group, especially, intraoperative PCO2 was increased due to CO2 retension and metabolic acidosis was developed, intraoperatively. PaO2 was excessively increased due to hyperventilation to correct the metabolic acidosis, intraoperatively. Satistically, intraoperative pH (p=0.0001), PaO2 (p=0.0001), PCO2 (p=0.0001) except bicarbonate (p=0.1987) were significantly changed, compared with preoperative pH or postoperative pH. 6. Operative cholangiography(OPC) was proceeded in 17 patients(14.2%) and concurrent laparoscopic appendectomy was done in 7 patients (5.8%) of the LC group. 7. Postoperative complications were occurred in 19 patients (15.8%) of the LC group. 3 patients (2.5%) were explorated, the remainders were recovered by conservative treatment. 8. On pathologic findings, cholelithiasis and chronic cholecystitis with 105 patients (87.5%) were most frequent in the LC group. In the OC group, cholelithiasis and chronic cholelithiasis with 25 patients (62.5%) were also most frequent, GB empyema with 8 patients (20%), acute cholecystitis with 7 patients (17.5%). Conclusively, laparoscopic cholecystectomy can be safely applied with lower morbidity, shorter operation times, and shorter hospital stay in selected patients.